New World screwworm flies cause disease primarily in animals and livestock, but humans can be infested. NWS was eradicated in the US and Americas; however, Panama, Costa Ria, Nicaragua, and Honduras have recently documented cases, causing concern about northward spread. During this COCA Call, a presenter outlines the biology of C. hominivorax, explains the current epidemiology, reviews guidance on how to identify infestations, and discusses how to manage and report cases of NWS in humans.

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